Here's how Mimosa describes itself:
In short, it's an amazing development and build tool for JS applications. If you wish to use it with Durandal, these steps will get your system set up:
npm install -g mimosa
mimosa skel:new durandal path/to/your/new/project/folder
Note: If you want mimosa to create the project in the current folder, simply execute the command without the path portion.
Note: Mimosa has an amazing feature set and extensive documentation. Please visit their official site to learn more and to troubleshoot Mimosa-specific issues.